Clinical trials

Condition   Drug Name  
Study (-)-Epigallocatechin gallate in rosacea
Design Randomized; Double-blind
Patients 14
Treatment Regimen (-)-Epigallocatechin gallate cream top. b.i.d. x 6 wks; Placebo
Conclusions (-)-Epigallocatechin gallate significantly downregulated hypoxia inducible factor-1 alfa and vascular endothelial growth factor expression even in the absence of clinical improvements in patients with rosacea
Reference(s) Epigallocatechin-galate infused cream has anti-angiogenic effects in rosacea
J Invest Dermatol 2007, 127 (Suppl. 1):Abst 23.
Author and Affiliation Santo Domingo, D., Camouse, M., Miller, J., Hsia, A.H., Ward, N.L., Matsui, M., Maes, D., Cooper, K.D., Baron, E.D.