Access Dermatology

A 46-year-old woman developed high fever and a widespread pruritic, erythematous pustular rash 4 days after taking antibiotics for an exacerbation of chronic maxillary sinusitis. Initially, oral cephalosporin was prescribed. Three days later, as there was no clinical improvement of sinusitis, amoxicillin was started. Twelve hours later, the patient noticed severe facial flushing. The next day she developed a pruritic erythematous eruption over her face, trunk and extremities with rapidly spreading pustules...