Systemic lupus erythematosus is an
autoimmune, inflammatory, connective tissue disease occurring in
flares and remissions. It can affect almost any organ system. The
skin changes appear mostly in sun-exposed areas of the face and
arms in the form of diffuse or macular erythema, which on the face
is known as malar rash. Among other organ involvement, disorders of
the musculoskeletal, hematopoetic, cardiac, pulmonary, renal or
neural system are the most common. The differential diagnosis
includes dermatomyositis, systemic scleroderma or mixed connective
tissue disease...