Access Dermatology

Systemic lupus erythematosus is an autoimmune, inflammatory, connective tissue disease occurring in flares and remissions. It can affect almost any organ system. The skin changes appear mostly in sun-exposed areas of the face and arms in the form of diffuse or macular erythema, which on the face is known as malar rash. Among other organ involvement, disorders of the musculoskeletal, hematopoetic, cardiac, pulmonary, renal or neural system are the most common. The differential diagnosis includes dermatomyositis, systemic scleroderma or mixed connective tissue disease...