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Treatment of pediatric atopic dermatitis in patients with specific IgE and IgG4 to cow’s milk

Treatment of pediatric atopic dermatitis in patients with specific IgE and IgG4 to cow’s milk

 
 

The influence of the probiotic Lacidofil (95% L. rhamnosus Rosell-11 and 5% L. Rosell-52) on the clinical course and Ig profile to cow's milk in infants (<4 years old) with atopic dermatitis (AD) was studied. The treatment group (n=30) received Lacidofil and Trixera emollient cream and bath. The control group (n=30) received the same treatments except for malto-dextrin instead of Lacidofil. Outcome measures were the SCORing Atopic Dermatitis (SCORAD) index, total IgE, and specific IgE, and IgG4 to cow's milk. The treatment group had a significant decrease in SCORAD (p<0.01), while the controls almost achieved significance versus baseline (p=0.05). Total IgE was unchanged in both groups. However, specific IgE decreased in the ...

 
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