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Evaluation of IgA antibodies in dermatitis herpetiformis


Specific IgA antibodies to tissue transglutaminase (TG2) and to epidermal transglutaminase (TG3) were measured in patients with dermatitis herpetiformis (DH), celiac disease (CD) and controls. Levels of IgA-TG2 antibodies were higher in DH and CD patients compared to controls. IgA-TG2 antibodies were higher in children with CD compared with adults with CD and DH and control subjects. IgA-TG3 antibodies were higher in patients with DH and adults with CD, compared with children with CD and controls. There was a trend towards higher levels in DH patients compared with adult CD patients (Hull, C.M. et al. Br J Dermatol 2008,159[1]: 120-124). --> -->

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