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Two potential new biomarkers for atopic dermatitis found in humans


Researchers at the Translational Research Center and the SUN General Hospital in Daejeon, Korea used a proteomic approach to search for efficient markers of atopic dermatitis (AD) in plasma. Human plasma samples were taken from healthy donors and AD patients aged 2-7 years old. Compared to healthy donors, significant quantitative changes in the pattern of expression of glycoproteins were found in plasma samples from AD patients. Sequential studies found that AD was associated with increased expression of CD5L and reduced expression of apolipoprotein E (ApoE). These results suggest that both CD5L and ApoE may be potential biomarkers of AD. Further studies are needed to determine the role of the altered levels ...

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