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Evaluating out-in skin transparency in atopic dermatitis


A new method for evaluating outside to inside (out-in) skin transparency was assessed using food dyes, namely tartrazine, and a colorimeter. Two studies were conducted. One in 24 normal and 4 atopic dermatitis (AD) patients assessed the relationship between skin color and atopic dermatitis score. This was positive and significant (r = 0.529; p = 0.001). Other parameters such as transepidermal water loss (TEWL), moisture content on the skin surface and stratum corneum were not correlated. In study 2, the skin transparency index (STI) was evaluated in 38 AD patients, 27 patients with dry skin and 29 healthy controls. The STI in AD patients was higher than in controls or in ...

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