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Methotrexate use in psoriasis: An update on national guidelines


A consensus view on newly updated guidelines since 1998 on the use of methotrexate for psoriasis was published. The review considered efficacy, contraindications, pre-methotrexate evaluation, laboratory studies, drug-dose schedules, folate supplementation, hemotoxicity and hepatoxicity, liver biopsy results, combination and rotational therapies, overdosage, low dose methotrexate in pregnancy, pediatric use and drug interactions (Kalb, R.E. et al. J Am Acad Dermatol 2009, 60(5): 824).

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