Breaking News


Effects of oral naltrexone on pruritus in atopic eczema: A controlled study


A 2-week, double-blind, randomized, placebo-controlled study recruited 38 acne vulgaris patients (24-85 years) suffering from pruritus to evaluate the effects of naltrexone (50 mg/day). Pruritus was assessed at baseline, weeks 1 and 2 using a 0-10 visual analog scale. Naltrexone was significantly more effective than placebo on pruritus at week 1 (P < 0.005) and week 2 (P < 0.001). Two patients in the naltrexone group had sedation and nausea; one patient in the placebo group reported nausea. Further, larger studies are warranted (Malekzad, F. et al. JEADV 2009, 23(8): 948).

to Continue Reading, Login Now

Please Login

If you are a registered user but you have forgotten your password, please click here
If you are not a registered user, please register here

return to breaking news list