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Serum levels of thymus and activation-regulated chemokine CCL17 in pediatric atopic dermatitis


A Japanese study attempted to determine normal levels of the thymus and activation-regulated chemokine (TARC) CCL17 in infancy in nonatopic controls and in those with atopic dermatitis (AD) aged less than 6 years (n = 27) and those 6 years and older (n = 18). CCL17 levels were also correlated with the SCORIng Atopic Dermatitis index (SCORAD). Serum levels of CCL17 were significantly higher in younger than older nonatopic subjects (P < 0.01). The cut-off values of CCL17 were 1,431, 803 and 510 pg/mL for the 0-1, 2-5 and 6 years and older AD groups, respectively. CCL17 levels also correlated with the SCORAD index across the age groups (r = ...

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