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Health-related utility among adults with atopic dermatitis with topical tacrolimus as long-term maintenance therapy

 
 

Health-related utility changes were assessed with the use of twice-daily tacrolimus ointment 0.1% or vehicle in 257 patients with mild-severe atopic dermatitis (AD). Patients had been treated for 12 months in a double-blind fashion. Health-related utility was assessed using the EuroQoL index (the EQ-5D). At the end of treatment a mean change of 0.045 units (adjusted for age and gender) was seen in the tacrolimus group compared with those treated with vehicle (P < 0.001). Patients with AD of all severities showed considerable decreases in health-related utility and this was significant for patients with both moderate and severe AD (Poole, C.D. et al. Br J Dermatol 2009, 161(6): 1335).

 
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