The final presentation of Session V of the XX International Clinical Dermatology Meeting of Barcelona, a session dedicated to the discussion of current research topics in the field of dermatology, was given by Dr. John A. McGrath from St. John's Institute of Dermatology at King's College London. Dr. McGrath underlined the importance of two fundamental aspects in genodermatosis research: diagnosis, which he described as "the challenging, satisfying part" and treatment, which he referred to as "the difficult bit". The main goal in this field of research is to identify genes associated with monogenic diseases in order to gain insight into the pathology of these conditions, the benefit of which would be ...