An introduction to the review by Paul, C. et al. (JEADV 2010, 24(Suppl. 2): 2-9) has been published. The aims of the guidelines were to integrate psoriasis progress into optimal clinical practice and to critically appraise the evidence. Disease severity, quality of life and comorbidities were the focus of the guidelines as well as to subject their recommendations to group evaluation and rating. Levels of evidence, the degree of agreement and impact on clinical practice were also assessed (Paul, C., Ortonne, J-P. JEADV 2010, 24 (Suppl.2): 1).