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Application of DAREA/DAPSA score to assess psoriatic arthritis disease activity

The reliability and validity of a questionnaire, the Disease Activity Index for Reactive Arthritis (DAREA), originally developed for reactive arthritis, was assessed in patients with psoriatic arthritis (PsA). Trial data from 180 patients in the Infliximab Multinational Psoriatic Arthritis Controlled trial (IMPACT) were analyzed and independently validated and a real-life cohort of 99 PsA outpatients was also studied. A good correlation was obtained between the DAREA with single items of disease activity, other composite scores (r = 0.6-0.9) and physical activity on the Health Assessment Questionnaire (r = 0.5). DAREA also correlated well with radiographic changes. In view of these findings, an alternative name for the questionnaire, the Disease Activity index for ...