A German population-based, cross-sectional study using a postal questionnaire assessed the point, 12-month and lifetime prevalence of chronic pruritus in 2,540 patients. Its association with sociodemographic variables and its characteristics were also assessed. The point, 12-month and lifetime prevalence of chronic pruritus was 13.5, 16.4 and 22.0%, respectively. Ethnic origin was independently associated with chronic pruritus. Disease severity appeared to impact quality of life and emotional well-being. This report indicates a high societal burden for chronic pruritus, although the self-report and potential self-selection aspects of the study are caveats (Matterne, U. et al. Acta Derm Venereol 2011, 91: 674).