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Study of pemphigus vegetans finds no correlation between clinical findings and prognostic outcome

Study of pemphigus vegetans finds no correlation between clinical findings and prognostic outcome

 
 

A Tunisian retrospective study (1981-2009) of 17 cases of pemphigus vegetans was conducted to analyze epidemiological, clinical, immunopathological and therapeutic data. Hospital prevalence was 0.084% with a frequency of 9.1% among patients with pemphigus. Mean age at presentation was 47.6 years with a 4.66:1 male:female ratio. Neumann pemphigus vegetans was the most common form in 11/17 patients; lesions were multifocal in 16/17 patients and mainly present on folds and mucous membranes. Corticosteroids healed the lesions in a mean of 24 days; during follow-up 3 patients died and 11 patients relapsed. The median overall relapse-free survival was 13 months. No correlation between clinical data and prognostic outcome was found (Zaraa, I. et ...

 
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