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Topical urea, lactic acid and propylene glycol formulation improves symptoms of scalp seborrheic dermatitis
Topical urea, lactic acid and propylene glycol formulation improves symptoms of scalp seborrheic dermatitis
Two multicenter, randomized, double-blind, vehicle-controlled studies were conducted with K-301 (Kaprolac[R]) containing urea, lactic acid and propylene glycol in the treatment of scalp seborrheic dermatitis. Another version of K-301 (K-301b) containing isopropyl alcohol was also tested in one study. In study 1 patients were randomized to K-301 and K-301b (n = 51) or vehicle (n = 47) for once-daily treatment for 4 weeks followed by 4 weeks of maintenance treatment 3 times/week. In study 2, patients were randomized to 4 weeks of K-301a once daily (n = 136) or vehicle (n = 65). The erythema and desquamation score at week 4 was the primary endpoint in both studies. The mean ...
Last updated: Tuesday, November 29, 2011
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ISSN 2013-8202
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