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Adiposity correlated with psoriasis severity in Japanese patients

To evaluate the association between obesity/adiposity and psoriasis in Japanese psoriasis patients, 122 patients were enrolled into a study in which body mass index (BMI), percent body fat (%BF) and visceral adiposity were assessed along with plasma levels of adipocytokines. BMI, %BF and visceral adiposity were all increased in the psoriasis patients compared to a control group of 78 healthy subjects. The obesity measures were correlated with Psoriasis Area and Severity Index (PASI) severity, with a higher correlation was seen with %BF and visceral adiposity than with BMI. In addition, plasma adiponectin levels in psoriasis patients were negatively correlated with BMI, %BF and visceral adiposity, while plasma levels of TNF-alpha and ...