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Probiotics during weaning reduce eczema incidence

Probiotics during weaning reduce eczema incidence


A double-blind, randomized, placebo-controlled trial to evaluate the effects of probiotics (Lactobacillus F19; LF19) on the incidence of eczema in infants (37-42 weeks old) was conducted. The infants were fed cereals with (n = 89) or without (n = 90) LF19 from 4-13 months of age. The cumulative incidence of eczema was determined at 13 months. It was found that the incidence of eczema was halved from 22% in the control group to 11% in the probiotic group (P < 0.05). The number-needed-to-treat value was 9. There were no differences in serum IgE levels between groups. However the interferon-gamma/interleukin 4 mRNA ratio was significantly higher in the probiotic group (P < ...

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