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ESMO clinical practice guidelines for primary cutaneous lymphomas

ESMO clinical practice guidelines for primary cutaneous lymphomas


The European Society for Medical Oncology (ESMO) guidelines for primary cutaneous lymphomas (PCLs) were recently published; these supersede those published in 2009. First-line recommendations for primary cutaneous marginal zone lymphoma (PCMZL), solitary/localized types, were local radiotherapy, excision and antibiotics (if Borrelia burgdoferi infection was present). If multifocal PCMZL was present, a "wait and see" approach, local radiotherapy or chlorambucil was indicated. For solitary/localized primary cutaneous follicle center lymphoma (PCFCL), the first-line approach should be rituximab, local radiotherapy and excision and for multifocal PCFCL, a "wait and see", local radiotherapy and i.v. rituximab were  recommended. For primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL-LT) of solitary/localized type, rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) with ...

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