Clinical Cases

A Nonhealing Leg Ulcer

A Nonhealing Leg Ulcer




An 85-year-old woman was referred with a 5-year history of a nonhealing ulcer on the right lower leg. The ulcer had not responded to consistent conservative treatment, compression therapy and split-thickness skin grafting. Her medical history was remarkable for chronic venous insufficiency and posttrombotic syndrome of the right lower leg. Additionally, she had hypertension, arrhythmia, myocardial hypertrophy, glaucoma and type 2 diabetes mellitus. Her medications included nitroglycerin, methyldigoxin, atenolol, amlodipine, aspirin and metformin. The patient denied any arsenic exposure, irradiation or burns. She had no positive history of skin cancer.

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