Introduction
Summary
Autoimmune blistering disorders
such as pemphigus have been associated with an increased incidence
of malignancy. The exact pathogenesis of this association is not
well understood. We report a case of pemphigus vulgaris associated
with carcinoid tumor and liver metastasis. Pemphigus lesions showed
an excellent response to dexamethasone cyclophosphamide pulse
therapy irrespective of the course of the underlying
malignancy.
Introduction
The association between pemphigus
and malignancy can have different presentations. Paraneoplastic
pemphigus (PNP) is a well-defined subset of this association, but
many cases do not fulfill the criteria for PNP. Malignancy can
develop in patients with pemphigus as result of chronic irritation
and ulceration and, conversely, pemphigus can develop in patients
with malignancy secondary to induction by radiotherapy and
chemotherapy.
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