A study conducted at St. Thomas' Hospital in London and the University of Manchester in the UK compared the rates of atopic dermatitis in patients with allergic contact dermatitis caused by fragrance chemicals on oral/cutaneous exposure, and those with the disease caused by fragrance chemicals on cutaneous exposure alone, out of a sample of 37,065 dermatitis patients tested between 1982 and 2007. The rates of atopic dermatitis in patients allergic to fragrances on significant gastrointestinal exposure (e.g., cinnamic alcohol or cinnamal) were 9.0% and 10.4%, respectively, for current dermatitis, and 16.5% and 19.2%, respectively, for past dermatitis (determined by a history of involvement of the flexures in childhood). In patients allergic ...