Summary
Recent advances in the pathogenesis and management of Sjogren
syndrome are summarized in this review, including major topics such
as newly described pathomechanisms and cutaneous manifestations of
Sjogren syndrome including annular erythema, recurrent purpura,
prevalence of eyelid dermatitis, mechanisms on photosensitivity and
hypohidrosis seen in Sjogren syndrome. On the management of Sjogren
syndrome, clinical effect of newly marketed M3 muscarine receptor
agonist on sicca symptoms is briefly summarized. Because Sjogren
syndrome is a relatively underestimated collagen disease in
contrast to systemic lupus erythematosus, systemic sclerosis or
dermatomyositis, special care should be taken not to misdiagnose
Sjogren syndrome when we see the patients with common skin disease
such as drug eruption, infections skin disease or xerosis in the
daily practice.