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Study identifies factors associated with psoriatic arthritis development in psoriasis patients

The incidence of new-onset psoriatic arthritis and predictors of its development in patients with psoriasis were determined in a population-based cohort of 1,593 subjects, and medical records covering a 30-year period were analyzed. In a total of 20,936 person-years of follow-up, 57 subjects developed new-onset psoriatic arthritis, a rate of 2.7 per 1,000 person-years and a cumulative incidence of 1.7, 3.1 and 5.1% at 5, 10 and 20 years, respectively, following psoriasis incidence. The psoriasis features significantly associated with an increased risk of psoriatic arthritis were scalp lesions (HR 3.89), nail dystrophy (HR 2.93) and intergluteal/perianal lesions (HR 2.35). The risk of psoriatic arthritis increased with the number of affected sites, ...