A French, cross-sectional, multicenter study of 590 patients with plaque psoriasis was conducted to evaluate the impact of the disease on personal and professional life and to evaluate the cost/patient/year. Quality of life was evaluated by the Dermatology Life Quality Index (DLQI) and productivity loss by the Working Productivity and Activity Impairment-Psoriasis (WPAI) questionnaire. The mean DLQI was 8.5 and 6.4 for patients with severe and mild psoriasis, respectively. Global loss of productivity was 10.7% irrespective of disease severity. Daily activity alterations were 36.8 and 19.6% for patients with severe and mild disease, respectively (P = 0.002). The time required for phototherapy was 33 h/year/patient and for emollient application, 25 h/year/patient. The ...