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A dermoscopy follow-up of slow-growing melanoma

A multicountry, multicenter retrospective study of 103 melanomas from 96 patients evaluated clinicodermoscopic features and growth patterns at baseline and a median follow-up of 20 months. Most lesions were still in situ or early invasive with only three lesions showing a tumor thickness of 1 mm or more. At baseline the most frequent characteristics were asymmetrical pigmentation, a reticular overall pattern and regression features. Most (58.3%) melanomas showed only minor-moderate changes over time with < 2 mm increase with asymmetrical changes. Major changes were only apparent after a mean follow-up of 33 months (Argenziano, G. et al. Br J Dermatol 2010, 162(2): 267).