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Patients with atopic dermatitis show neuronal sensitization to itch in nonlesional atopic skin

Patients with atopic dermatitis show neuronal sensitization to itch in nonlesional atopic skin

 
 

A total of 24 healthy controls without atopy and 24 patients with atopic dermatitis (AD) participated in a study evaluating the efficacy of neuroselective transcutaneous electrical stimulator (NTES) in evaluating and characterizing itch and pain perception. Significant differences in the sensations evoked by the NTES were observed between participants, and itch sensation was more frequently evoked in nonlesional skin of patients with AD than in healthy controls. Quantitative and qualitative differences between the study groups were also observed as regards the minimum itch perception, the minimum pain thresholds and the current perception threshold on several body sites with lower current perception threshold on the lateral aspect of the antecubital fossae, the flank ...

 
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